Correction: Fish oil: what the prescriber needs to know

نویسندگان

  • Leslie G Cleland
  • Michael J James
  • Susanna M Proudman
چکیده

It has been brought to our attention that there were a number of typographical errors in one section of our recent article [1] published in December 2005. All corrections apply to the section entitled, 'Biochemical rationale; Eicosanoids: cyclo-oxygenase pathway'. The second paragraph should read: The usual substrate for the COX isozymes is the n6 LC PUFA arachidonic acid (AA; C20:4n-6). Eicosapentaenoic acid (EPA; C20:5n-3), which is present in fish oil, differs from AA only by the presence of its n3 bond (Fig. 1). The last sentence of the third paragraph should read: Thus, the net effect of fish oil is to reduce the production of proinflammatory and pro-thrombotic eicosanoids (PGE 2 and TXA 2 , respectively) but not the vascular patency factor prostacyclin (PGI 2 ; Fig. 2). Finally, the first 20-Carbon fatty acid homologue pictured in Figure 1 (C20:3 n-9) is eicosatrienoic acid, rather than oleic acid.

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عنوان ژورنال:
  • Arthritis Research & Therapy

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2006